This image shows Viviane Klingel

Viviane Klingel


Research Assistant
Institute for Stochastics and Applications
Mathematical Modeling and Simulation of Cellular Systems
[Photo: Ludmilla Parsyak, © Fraunhofer IAO]


+49 711 685 60454
+49 711 685 67735


Pfaffenwaldring 9
70569 Stuttgart
Room: 2.241

Office Hours

With appointment in my Webex room.


I work in the field of Systems Biology where I currently focuse on the modeling of an epigenetic memory system.

  1. Klingel, V., Graf, D., Weirich, S., Jeltsch, A., & Radde, N. E. (2022). Model-Based Design of a Synthetic Oscillator Based on an Epigenetic Methylation Memory System. ACS Synthetic Biology, 11(7), Article 7.
  2. Wagner, V., Höpfl, S., Klingel, V., Pop, M. C., & Radde, N. E. (2022). An inverse transformation algorithm to infer parameter distributions from population snapshot data. IFAC-PapersOnLine, 55(23), Article 23.
  3. Graf, D., Laistner, L., Klingel, V., Radde, N. E., Weirich, S., & Jeltsch, A. (2022). Reversible switching and stability of the epigenetic memory system in bacteria. The FEBS Journal.
  4. Adam, S., Bräcker, J., Klingel, V., Osteresch, B., Radde, N. E., Brockmeyer, J., Bashtrykov, P., & Jeltsch, A. (2022). Flanking sequences influence the activity of TET1 and TET2 methylcytosine dioxygenases and affect genomic 5hmC patterns. Communications Biology, 5(1), Article 1.
  5. Klingel, V., Kirch, J., Ullrich, T., Weirich, S., Jeltsch, A., & Radde, N. E. (2021). Model-based robustness and bistability analysis for methylation-based, epigenetic memory systems. The FEBS Journal, 288(19), Article 19.
  6. Broecker, J., Klingel, V., Ou, W.-L., Balo, A. R., Kissick, D. J., Ogata, C. M., Kuo, A., & Ernst, O. P. (2016). A Versatile System for High-Throughput In Situ X-ray Screening and Data Collection of Soluble and Membrane-Protein Crystals. Crystal Growth & Design, 16(11), Article 11.
  7. Broecker, J., Morizumi, T., Ou, W.-L., Klingel, V., Kuo, A., Kissick, D. J., Ishchenko, A., Lee, M.-Y., Xu, S., Makarov, O., Cherezov, V., Ogata, C. M., & Ernst, O. P. (2018). High-throughput in situ X-ray screening of and data collection from protein crystals at room temperature and under cryogenic conditions. Nature Protocols, 13(2), Article 2.
  • Teaching assistant for Grundlagen der Systembiologie (WS1920, WS2021, WS2122, WS 2223)
  • Teaching assistant for Stochastische Prozesse und Modellierung (SS19, SS20, SS21, SS22, SS23)
  • Teaching assistant for Dynamik biologischer Systeme (WS2021, WS2223)
  • Teaching assistant for Methoden in der Systembiologie (WS2122, WS2223)

since 02/2019

Research assistant at the Institute for Stochastics and Applications and at the Institute for Systems Theory and Automatic Control, University of Stuttgart, Germany.


Master studies in Technical Biology at the University of Stuttgart, Germany

  • Master thesis:
    "Feedback control of PKD activity and Golgi secretory function by the tumor suppressor DLC1"


Student assistant at the Institute of Biomaterials and Biomolecular Systems and Institute for Theoretical Chemistry.


International internship and Bachelor thesis at the University of Toronto, Canada.


Bachelor studies Technical Biology at the University of Stuttgart, Germany

  • Bachelor thesis:
    "Advances in in situ in meso X-ray Crystallography"


Abitur at the Lise-Meitner Gymnasium, Königsbach-Stein, Germany


Exchange Year at Thatcher High School, Thatcher, Arizona, USA


The Best SimTech PhD Student Publication 2020/2021


BC2, Basel, 2021
SBMC, Heidelberg, 2022
FOSBE, Boston, 2022
ICSB, Berlin, 2022

Supervision of Student Theses:

1 Master Thesis
4 Bachelor Theses
1 Internship

As a representative of doctoral students member of:

  • University Senat since 2020
  • Faculty Council of Faculty 7 Dec. 2020 - Sept. 2022
  • Senate Committee for Structure since 2021
  • Senate Committee for Diversity and Equal Opportunities since 2021

Board member of the doctoral student representation DOKUS since 2020

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